Perm Tech scientist together with Israel colleagues developed the computing model, which demonstrates how the tumor structure appears. The system will allow to predict how disease will be worsening and which medical treatment should be chosen for certain patient.
Blastoma is a heterogeneous tumor. But there is no idea how the structures of the certain tumors appear. Using the computing model Perm Tech scientists explained all these processes and defined the behavior of the tumor structures.
Heterogeneity of the tumor structures means that cells have their own functions performed by them during the growth of the tumor. For example there are cells which block the treatment process or there are cells which are in charge of uncontrolled growth of the tumor. Also there are mobile cells acting as a local metastases.
The model will allow to define conditions and mechanisms on how the tumor structures are developing and as a result to predict the certain type of the tumor in early stage. The forecasting of the tumor behavior will help doctors to choose the correct treatment for specific tumor structure.
The results of the research are published in the international scientific journal Biomechanics and Modeling in Mechanobiology.